Ko 143 from medchemexpress

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        Ko 143 is potent and selective breast cancer resistance protein multidrug transporter (BCRP) inhibitor (EC90 = 26 nM). Ko 143 displays > 200-fold selectivity over P-gp and MRP-1 transporters. Ko 143 increases intracellular drug accumulation and reverses BCRP-mediated multidrug resistance.