2014年7月17日星期四

Apoptosis |medchemexpress


The cells in the human body is doomed to death, some deaths are physical in nature, some deaths are pathological, research on cell death, has become a hot biology, medical research. People have been known to cell death are at least two ways, namely cell necrosis and apoptosis (apoptosis). Cell necrosis has long been recognized that a cell death, apoptosis and cell death is a way of gradually being recognized. 
Apoptosis is a fundamental biological phenomenon cells play essential roles in multicellular organisms eliminate unwanted or abnormal cells. It plays an important role in the evolution and development of the organism, and the environment within which the plurality of system stability. Apoptosis is not only a special type of cell death, but also has important biological significance and complexity of the molecular mechanisms. 
Apoptosis is a carefully controlled process of multiple genes. These genes are highly conserved between species, such as Bcl-2 family, caspase family of oncogenes such as C-myc, tumor suppressor gene P53, etc. With the development of molecular biology techniques for a variety of apoptotic process has considerable knowledge, but so far the exact mechanism of apoptosis is not fully understood. The disordered apoptosis may have a direct or indirect relationship with the occurrence of many diseases. Such as cancer, autoimmune diseases, can induce apoptosis of many factors, such as radiation, drugs. 
Part of the physical structure of a natural person apoptosis, such as human tail phase, the tail automatically apoptosis during development.
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